Figure 5 - full size

 

Figure 5.
Fig. 5. Dimerization surfaces. Stereo view of the superposition of core domain regions that form the symmetrical dimer interface upon DNA binding (one-half of the symmetrical dimer), including the nine structures of Fig. 1 (with the same color code) and the thermostable mutant T-p53C-R249S (PDB code 2BIO)^38 shown in light blue. The various structural elements (L2, L3, H1, H1″) and the boundaries of the corresponding regions (residues 168–195 and 236–250) are indicated. Zinc atoms are shown by the corresponding colored spheres.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2009, 385, 249-265) copyright 2009.