Figure 5.
Figure 5. Key elements for the hydrogen-bonding pattern of an
ATP-mimetic compound. The orientation of R3-O of the group A
kinase is more favorable for that of the group B kinase because
of the difference in the length of the specificity linker.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2008,
73,
795-801)
copyright 2008.
