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Figure 5.
Superposition of Pol II, III, and IV peptides and RU7
compound bound to β. (A) Superposition of the Pol III peptide
(green), Pol II peptide (blue), and Pol IV peptide (purple; PDB
ID code 1OK7) (10). (B) Superposition of Pol III peptide (green)
and the RU7 compound (orange). The surface of the β-clamp is
colored white, and the protein-binding pocket of β is colored
according to sequence conservation of an alignment of 42
bacterial subunits; the color scale proceeds from red (90%
conservation) to yellow (50% conservation). Circled regions in
the peptide-binding pocket indicate subsites 1 and 2. Figures
were prepared by using Pymol (27).
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