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Figure 5.
Interactions of the metal-binding domain and disaccharide
with the DNA. (A) Stereodiagram of the minor groove of DNA
(gray) shown with the metal-binding (yellow with Co in green)
and disaccharide (purple) domains and a modeled peroxide ligand
(cyan) as a ball-and-stick model. Hydrogen bonds are represented
as dashed lines with interacting O atoms in red and N atoms in
blue. Intermolecular bonds are black, intramolecular bonds are
blue, and magenta bonds represent interactions of the
propionamide as modeled (the propioanamide is absent in electron
density). The red stick indicates the connection to the linker
domain. (B) Schematic showing the hydrogen-bonding interactions
of the metal-binding and disaccharide domains in the minor
groove with bonds colored as in A.
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