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Figure 5.
Fig. 5. (a) A schematic diagram featuring differences in the
G-strand (red) between classic V-set Ig fold (left panel) and
Siglec-specific Ig fold (right panel). Sia is shown as a
β-strand (green). (b) Schematic representation of conserved
main chain interactions between Siglec CFG β-sheet and Sia
(green). The mode in which Sia interacts with main chain atoms
on the G-strand mimics hydrogen bond interactions (dashed lines)
in classic antiparallel pleated β-sheet.
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