Figure 5.
(a) Pol II stalling at the cisplatin lesion (this study),
shown as a schematic representation of RNA extension in complex
A. The initial RNA (top) corresponds to the unextended RNA of
scaffold A. Dashed line represents translocation barrier. The
artificial conditions leading to lesion bypass are depicted at
the bottom. (b) Pol II stalling at a CPD lesion. Schematic is
adapted from reference 8.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(2007,
14,
1127-1133)
copyright 2007.
