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Figure 5.
Hydrogen bonding interactions between Dpo4 and the 8-oxoG
lesion.A, R332A(8-oxoG:A); B, R332A(8-oxoG:C); C,
R332E(8-oxoG:A); D, R332E(8-oxoG:C); E, wild type 8-oxoG:dATP;
F, wild type 8-oxoG:dCTP. The protein is shown with schematic
α-helices and β-strands. The DNA duplex and selected Dpo4
residues are shown in stick mode. Ca^2+ ions and water molecules
are shown as yellow and red spheres, respectively, and hydrogen
bonds as dashed lines.
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