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Figure 8.
Figure 8. Aromatic interactions observed between Phe140 and
His163 in the crystal structures of SARS-CoV M^pro (wild type
and variants). The broken lines indicate the alignment of the
partial positive charges (δ+) of the hydrogen atoms on the
phenyl ring of Phe140 with the partial negative charges (δ−)
in the central part of the imidazole ring of His163.
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