Figure 5.
Figure 5. The nucleotide position slips between the GDP and
GMPPCP states. Following superposition of the FtsY:GDP monomeric
and FtsY:GMPPCP complexed states of FtsY over the motif I P-loop
(at right), the -
and -phosphate
groups of GDP and GMPPCP (labeled) remain fixed relative to each
other, but the ribose and the guanine base shift by 1
Å between the two structures (1.04 Å at the 2-amino
nitrogen, as indicated). This slip is tracked by movement of the
motif IV loop and by the specificity determining carboxylate
sidechain of Asp^258.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2007,
66,
984-995)
copyright 2007.
-
and 
-phosphate
groups of GDP and GMPPCP (labeled) remain fixed relative to each
other, but the ribose and the guanine base shift by 
1
Å between the two structures (1.04 Å at the 2-amino
nitrogen, as indicated). This slip is tracked by movement of the
motif IV loop and by the specificity determining carboxylate
sidechain of Asp^258.