Figure 5 - full size

 

Figure 5.
Figure 5. Proposed Mechanism for FeeM
This mechanism is based on aspects of GNAT function and the similarity between FeeM and AANAT. The sequence of proton transfers shown, which is somewhat arbitrary, indicate plausible general bases in the active site. FeeL is the ACP with which FeeM interacts.

The above figure is reprinted by permission from Cell Press: Structure (2006, 14, 1425-1435) copyright 2006.