Figure 6 - full size

 

Figure 6.
Figure 6. Stereo view of the Ni^2+-binding site in the 70–80 loop of hK4, superimposed by the equivalent segments of hK1 in grey. The Ni^2+ is shown as a cyan ball, bound by four water molecules, Glu77 O^ε, and His25 N^ε2. The Ni^2+ ligand contacts are depicted as dotted lines. The electron density accounting for the coordinating water molecules is contoured at 1.0σ and that around nickel at 5.0σ. The most significant difference between the compared loops is one helical turn in hK4.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2006, 362, 1094-1107) copyright 2006.