Figure 5 - full size

 

Figure 5.
Figure 5 Detailed interaction between me2K4 in H3K4me2 and Glu322 in WDR5. (A) The H3K4me2 peptide and WDR5 are colored in yellow and blue, respectively. The electron density map is contoured at 1 . Potential water-mediated hydrogen bonds are shown as dashed orange lines. (B) The lower panel shows schematics of two alternative hydrogen binding networks involving the water molecule.

The above figure is reprinted by permission from Macmillan Publishers Ltd: EMBO J (2006, 25, 4245-4252) copyright 2006.