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Figure 5.
FIGURE 5. Modeling the rCD48-rCD2 complex. A, two
orthogonal views of a ribbon representation of the likely
complex formed between the full extracellular domains of rat CD2
(blue) and rat CD48 (green, modeled on cCD48). B, expanded view
of the interface, with the side chains of the residues most
likely to be involved in the interaction shown as ball-and-stick
representations. Hydrogen bonds are shown as dashed red lines.
C, comparison of the modeled rat CD2-CD48 complex (left) with
the solved human CD2-CD58 complex (right, CD58 in red). The
solvent-accessible molecular surface of the separate proteins is
shown semi-transparently over a representation of their
secondary structure to illustrate the complementarity of the
binding surfaces.
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