Figure 5 - full size

 

Figure 5.
Figure 5 Crystal structure of Tth Gfh1. (A) Ribbon representation of Gfh1 structure is shown in two orthogonal views (left and central panel). The location of the two domains, NTD and CTD, and the four Asp residues of NTD loop are indicated. The structure of E. coli GreA (Stebbins et al, 1995) is shown for comparison (right panel). (B) Superposition of the structures of E. coli GreA (orange) and Tth Gfh1 (blue) as C[ ]trace. Left panel shows the alignment by NTD and central panel shows alignment by CTD. Overall, the molecules superimposed well with r.m.s. deviation of the C[ ]atoms=1.8 Å with more than 90% equivalences. The rotation axis of the CTD is indicated. Right panel shows aligned NTDs, rotated by 60° counterclockwise around the NTD axis from the view shown in the left panel.

The above figure is reprinted by permission from Macmillan Publishers Ltd: EMBO J (2006, 25, 2131-2141) copyright 2006.