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Figure 5.
Fig. 5. Docking of the C-terminal myosin helix into the
hydrophobic groove of dynamin. (A) The structure of the dynamin
1-myosin fusion as solid cartoon with the dynamin 1 GTPase
domain drawn in dark gray, the groove helices  A and
5
in yellow and orange, respectively, and the myosin motor domain
in blue. The structure of the dynamin A fusion is superimposed
in transparent gray. Although the dynamin domains align well,
the myosin motor domains adopt different conformations in the
dynamin 1 and dynamin A fusion structures. (B) Schematic
representation of the hydrophobic interactions (solid lines
between the respective amino acid partners) between helices A
(yellow box) and 5 (orange box) and the
C-terminal myosin helix (blue box).
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