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Figure 5.
Fig. 5. Nucleotide binding to Arp3. (A) Overlay of Arp3
from ATP (yellow) and ADP-Arp2/3 (cyan) complexes based on the
superposition of the entire Arp3 subunit (as in Fig. 3B). ADP is
shown in magenta, and ATP is shown in blue. (B) Interactions of
ATP phosphates with Arp3. (C) Interactions of ADP phosphates
with Arp3. (D) Overlay of actin (PDB entry 1NMD [PDB]
, green) and ATP-Arp3 (yellow) based on superposition of the
entire molecules. ATP and divalent cation from the actin
structure are orange, ATP and Ca^2+ from Arp3 are blue. Select
water molecules from 1NMD [PDB]
are modeled as red spheres.
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