Figure 5.
Figure 5. The electron density map for the R116A fragment as a
semi-transparent rendering is superimposed on an overlay of the
side chains of the R116A (blue) and wild-type (red) fragment
structures at residue 116. The positions of the atoms for
residue 116 are remarkably similar including the C position
in the R116A fragment versus the wild-type structure.
Substitution of Arg for Ala at residue 116 in the N-terminal
fragment does not result in any conformational changes in the
fingers domain binding site nor anywhere else in the protein as
noted in Figure 4.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2004,
57,
15-26)
copyright 2004.
position
in the R116A fragment versus the wild-type structure.
Substitution of Arg for Ala at residue 116 in the N-terminal
fragment does not result in any conformational changes in the
fingers domain binding site nor anywhere else in the protein as
noted in Figure 4.