Figure 5 - full size

 

Figure 5.
Figure 5. Superimposition of the GTPase domains of YloQ and the Ras-GDPNP complex (PDB accession, 1LF0) as a stereo view. The ribbon tracing of YloQ is presented in cyan, that for Ras is in yellow. The guanine nucleotide bound in Ras is displayed in ball-and-stick format in magenta. The broken line indicates the disordered region in the YloQ molecule. The G1 (P-loop), G2 (Switch I), G3 (Switch II) and G4 (guanine specificity motif) segments of YloQ are coloured red. The structures were overlapped initially in the program MOLREP,[35.] and subsequently adjusted manually to emphasise similarities and differences in the P-loop region.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2004, 340, 767-782) copyright 2004.