Figure 5.
Figure 5. Open sandwich illustrations of the interaction
surfaces of AR proteins and their targets. (a -c) GRASP50
shape complementarity representations of the interactions
between off7 and MBP (shape complementarity, 0.739) (a), GABP
1
and GABP (PDB
entry 1AWC; shape complementarity, 0.665) (b), and p18^INK4c and
CDK6 (PDB entry 1G3N; shape complementarity, 0.688) (c),
respectively. The complex is shown on the left with the AR
proteins in a backbone worm representation ( -helices
in blue, -turns
in green) and the target protein in a surface representation.
The open sandwich surface representations are shown in the
middle (AR proteins) and on the right (targets). The contact
areas are stained according to the shape complementarities from
orange (low) to red (high).
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Biotechnol
(2004,
22,
575-582)
copyright 2004.
1
and GABP 
(PDB
entry 1AWC; shape complementarity, 0.665) (b), and p18^INK4c and
CDK6 (PDB entry 1G3N; shape complementarity, 0.688) (c),
respectively. The complex is shown on the left with the AR
proteins in a backbone worm representation (