Figure 5 - full size

Figure 5. FIG. 5. Comparison of crystal structures of wild type Ad12 knob-CAR D1 and Ad12 knob P417S-CAR D1. a, stereo figure showing part of the wild type Ad12 knob-CAR D1 interface including CAR D1 residues I55-E56-W57 (cyan) and Ad12 knob residues P416-P417-P418 (yellow); no hydrogen bonds are formed at this interface. b, stereo figure of same view of the interface between Ad12 knob mutant P417S (blue) and CAR D1 (red); note the novel hydrogen bond formed between Ser417 of knob and Glu56 of CAR D1.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2003, 278, 26208-26215) copyright 2003.