|
Figure 5.
Figure 5. The Binding of ATP-Bound HslU Opens the Central
Pore of HslV(a) Uncomplexed HslV has a closed pore [27].(b) The
binding of the ATP-bound HslU opens the central pore of HslV
with an average diameter of 19.3Å [27]. The HslU C terminus is
shown in magenta. The insertion of the C terminus and relative
twisting ring rotation may be responsible for the pore opening
in a "twist-and-open" mechanism. Two conserved arginines, Arg-86
and Arg-89, are also shown. There are two more positively
charged residues, which are not shown, nearby at the pore of
HslV (Arg-83 and Lys-90)
|
