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Figure 5.
Figure 5. Similarity in the Binding Modes of p21 and RB69
DNA Polymerase to the Interaction of δ with βThe structure of
the β subunit in the β:δ complex is shown in gray and cyan.
The structures of PCNA complexed to p21 (Gulbis et al., 1996)
(PDB code 1AXC) and gp45 of RB69 complexed to a segment of RB69
DNA polymerase (Shamoo and Steitz, 1999) (PDB code 1B8H) were
superimposed individually onto the structure of the β subunit
by using the β strands at this interdomain interface to overlay
the structures. The structure of the p21 peptide (orange) and
the RB69 DNA polymerase tethering segment (yellow) are shown,
but were not used in the structural superposition. The structure
of δ is shown in green. PCNA and gp45 are not shown
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