Figure 5 - full size

 

Figure 5.
Figure 5 (a) Superimposed -loop structures of AP, PP and EP: AP is in red, the PP-macrocycle complex is in blue and the EP-pepstatin complex is in yellow. The two ligands are drawn in thin lines. The labelled amino acids are those of AP. (b) Superimposed -loop structures of AP, RP, MP, CP and human pepsin: AP in red, RP in blue, MP in green, CP in pink and human pepsin in yellow. The labelled amino acids are those of human pepsin.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2001, 57, 948-956) copyright 2001.