Figure 5 - full size

 

Figure 5.
Figure 5 Coordination of the Mg2+ ion in wild-type Kar3. The bound Mg2+ of wild-type Kar3 has a tetragonal bipyramidal or octahedral coordination due to the P[ ]oxygen, the hydroxyl group of T481 and four water molecules that also interact with D626 of switch II (cyan), R585 and T587 of loop L9, and N593 of helix 3a. R585 is hydrogen bonded by a water molecule to the D626 side chain that interacts with the Mg2+.

The above figure is reprinted from an Open Access publication published by Macmillan Publishers Ltd: EMBO J (2001, 20, 2611-2618) copyright 2001.