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Figure 5.
Figure 5 Module reorganization upon dissection of 6F1^1F2^2F2.
Ribbon diagrams of the minimized average structures of (A)
6F1^1F2^2F2 and (B) 6F1^1F2. The colour scheme for the secondary
structure elements is as in Figure 3A -C. Side chains for which
6F1 -2F2 intermodule NOEs were observed (V10, Y12, S13, M16, L19
and L28 of 6F1, and L103, Q105, S111, N112, A114, L115, T145 and
K153 for 2F2) are shown in cyan for 6F1 and purple for 2F2.
Removal of the 2F2 module allows the side chain of Y68 (pink) in
1F2 to interact with L19 and L28 in 6F1.
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