|
Figure 5.
Figure 5. Surface Features of PolγB(A) Conserved residues
in PolγB from human, mouse, and Xenopus laevis. Residues of
mouse PolγB strictly conserved in human and at least
type-conserved in Xenopus are colored green (noncarbon atoms) or
yellow (carbon atoms). Residues of mouse PolγB deleted in
Xenopus PolγB are colored in magenta.(B) Surface potential of
the PolγB dimer calculated at neutral pH, ionic strength 100
mM, contoured at ± 10 kT (blue, positive; red, negative).
The surface potential of human PolγB (homology model, not
shown) is similar. Top, front view as in Figure 1B; bottom, view
of the C-terminal regions of PolγB. The arrows indicate the
pocket in domain 1.
|
