Figure 5 - full size

 

Figure 5.
Figure 5. Complimentarity between the interaction surfaces of hOSM and gp130. The solvent-accessible surfaces of site 2 on hOSM (left) and the cognate binding site on gp130 (right) are displayed with areas contributed by residues implicated in binding highlighted as coloured patches. The orientation for hOSM site 2 is rotated 90° from that in Figure 4 whereas gp130 is rotated by 180° from its orientation relative to hOSM in the putative interaction complex, as in the opening of a book.

The above figure is reprinted by permission from Cell Press: Structure (2000, 8, 863-874) copyright 2000.