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Figure 5.
Figure 5 Molecular surface properties of the radixin FERM
domain. (A) Surface electrostatic potentials of the radixin FERM
domain viewed from the same direction as in Figure 2A. Positive
(blue) and negative (red) potentials are mapped on the van der
Waals surfaces. The IP3 molecule found in the complex crystal is
shown in a stick model. (B) Surface electrostatic potentials
viewed along the arrow b in (A) to show the basic cleft between
subdomains A and C. The IP3 molecule found in the complex
crystal is shown in a stick model. (C) Surface electrostatic
potentials viewed along arrow c in (A) to show the acidic groove
between subdomains B and C. (D) A backside view of surface
electrostatic potentials seen in (A). The IP3 molecule found in
the complex crystal is shown in a stick model. (E) Conserved
residues of the radixin FERM domain mapped on the molecular
surfaces. A front view of the radixin FERM domain depicted as a
colored molecular surface using a gradient; orange indicates
conserved identical residues and white non-conserved residues,
while lighter shades of orange indicate semi-invariant residues.
A view from the same direction as in (A) and Figure 2A. (F) Back
view of conserved residues of the radixin FERM domain. (G) Front
view of hydrophobic residues of the radixin FERM domain mapped
on the molecular surfaces. (H) Back view of hydrophobic residues
of the radixin FERM domain.
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