Figure 5 - full size

 

Figure 5.
Figure 5 Schematic of hydrogen-bonded salt bridges of Molecumetics inhibitors with Asp189 of the S1 specificity site of thrombin. MOL354 and MOL1245 shown together in one schematic; values for MOL1245 are in parentheses.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2000, 56, 294-303) copyright 2000.