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Figure 5.
Figure 5. The Primary Interaction Site between FGF2 and
FGFR1(A) Stereo view of the hydrophobic interface between FGF2
and D2 of FGFR1. Only side chains of interacting residues are
shown. Color coding is the same as in Figure 1: FGF2 in orange,
D2 in green, D3 in blue, and the linker in gray. Dotted lines
represent hydrogen bonds.(B) Stereo view of the network of
hydrogen bonds between FGF2 and FGFR1 in the vicinity of Arg-250
in the D2–D3 linker.(C) Stereo view of the interface between
FGF2 and D3 of FGFR1. This figure was created using the programs
Molscript and Raster3D.
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