Figure 4 - full size

 

Figure 4.
Figure 4. S-adenosylhomocysteine-binding site in CheR. (a) A stereo diagram (MOLSCRIPT; [57]) of the AdoHcy-binding site. Only sidechain atoms are included in the figure except for the residues that form hydrogen bonds with AdoHcy through mainchain atoms. Hydrogen bonds are represented by dashed lines. (b) A schematic view of the contacts identified in the crystal structure of the CheR-AdoHcy complex. Hydrogen bonds are drawn with dashed lines and covalent bonds are shown as solid lines connecting the solid spheres that denote atoms. Residues within the hydrophobic pocket that accommodates the adenine portion of AdoHcy are represented by parallel curved lines. Sulfur atoms are shown in green, other atom colors are the same as Figure 2.

The above figure is reprinted by permission from Cell Press: Structure (1997, 5, 545-558) copyright 1997.