Figure 4 - full size

 

Figure 4.
Figure 4. Comparison of the Syp and Src SH2 domains. The polypeptide backbones of the Syp and Src SH2 domains are shown as red and white tubes, respectively. The YEEI peptide (Src) is shown in yellow and the IRS1-895 and PDGFR-1009 peptides (Syp) are shown in orange and blue, respectively. The view is approximately perpendicular to the peptide-binding surface. The two structures were first superimposed with the program O [44] and displayed using Insight (Biosym Technologies). Figure 4. Comparison of the Syp and Src SH2 domains. The polypeptide backbones of the Syp and Src SH2 domains are shown as red and white tubes, respectively. The YEEI peptide (Src) is shown in yellow and the IRS1-895 and PDGFR-1009 peptides (Syp) are shown in orange and blue, respectively. The view is approximately perpendicular to the peptide-binding surface. The two structures were first superimposed with the program O [[3]44] and displayed using Insight (Biosym Technologies).

The above figure is reprinted by permission from Cell Press: Structure (1994, 2, 423-438) copyright 1994.