Figure 4 - full size

 

Figure 4.
The cAMP induced conformational changes of CAP. The side view of CAP is shown. Structure of the unliganded CAP (Left) and of the liganded CAP (Right). A superposition of these two structures along their C-helices is shown in the middle of the figure. The unliganded structure is solid, whereas the liganded structure is transparent. To emphasize the conformational changes on cAMP binding, only the C-, D-, and F-helices are shown.