Figure 4 - full size

 

Figure 4.
Chemical shift mapping of UBA-Mex67 residues upon binding of FXFG and Hpr1. Normalized combined chemical shift difference Δδ upon binding of Hpr1-C (A) and the FXFG peptide (B) is mapped onto the structure of the UBA-Mex67 domain. Residues showing a normalized Δδ more than 0.6 upon binding of Hpr1 are shown in dark green, whereas residues that show a normalized Δδ more than 0.3 are shown in light green. Corresponding residues in the FXFG titrations are shown in orange and yellow. The position of the FXFG peptide is shown in blue. C, the same data mapped onto the sequence to enable direct comparison.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2009, 284, 17575-17583) copyright 2009.