Figure 4 - full size

 

Figure 4.
Figure 4. Comparison of Dpo4[Abasic.dCTP] and Polι[Abasic.dTTP] Ternary Complexes
The protein surface is displayed in light blue (Dpo4) or cyan (Polι), DNA is shown in stick representation, and putative Mg^2+ (Polι) or Ca^2+ (Dpo4) ions are shown as dark blue spheres. The abasic site and the incoming dTTP (Polι) or dCTP (Dpo4) are colored in red. The nucleotide 5′ to the abasic site in the Dpo4 complex is colored in sky blue. The abasic site is extrahelical in the Dpo4 complex (Ling et al., 2004), but remains intrahelical in the Polι complex(es).

The above figure is reprinted by permission from Cell Press: Structure (2009, 17, 530-537) copyright 2009.