Figure 4 - full size

 

Figure 4.
Comparison of polymerase active sites from the β-NT and classical superfamilies. The active sites and DNA substrates are shown from PolC (colored as in Fig. 1) and TaqDnaE (white; PDB ID code 3E0D) C family polymerases (A), Polβ (PDB ID code 2FMP), an X family polymerase (B), and RB69 (PDB ID code 1IG9), a B family polymerase (C). (B and C) Palms are colored magenta, and fingers are colored blue.