Figure 4 - full size

 

Figure 4.
Architecture of the interaction. (Center) Illustration of a top-view schematic of the ILK interaction with PINCH1. Three views show this interaction from different angles. (Left) Toward PINCH1 (gray surface) from the ILK ANK repeat finger side of the interaction. Lower images are toward PINCH1 (gray surface) from the ILK ANK repeat palm side of the interaction. (Right) Toward ILK (gray surface). Shown in red is PINCH1 backbone trace. Blown-up views show labels for residues involved in the interaction.