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Figure 4.
Comparison of the GC-1008 binding mode with type I and type
II TGF-β receptor binding. (A) Structure of the ternary TGF-β
signaling complex consisting of TGF-β3 bound to its type I and
II receptors. Structure is shown as depicted in ref. 14. (B)
Schematic comparison of GC-1008 binding versus receptor binding.
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