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Figure 4.
Putative SPARC-binding sites in collagen IV. Shown are
partial sequences of human collagen III (SwissProt entry P02461)
and collagen IV (α1 chain, P02462; α2 chain, P08572). The
SPARC-binding site in collagen III is highlighted; residues that
are predicted to be strictly required for SPARC binding (see
Prediction of SPARC-Binding Sites in Collagens I–IV) are in
red, residues that should be apolar are in orange. The same
coloring scheme is used to indicate the 4 putative SPARC-binding
sites in collagen IV.
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