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Figure 4.
Structure comparison of the Ca^2^+-bound form and Ca^2^+-free
form of the rabphilin-3A C2A domain. A, backbone superposition
of the Ca^2+-bound solution structure of the C2A domain (in
blue) with the Ca^2+-free crystal structure (in gray). B, Ca^2+
binding site comparison of the Ca^2+-bound form (in blue) with
the Ca^2+-free form (in gray). Backbones are represented by
ribbons, side chains of residues involved in Ca^2+ binding are
represented by sticks, and Ca^2+ ions are depicted as blue
spheres. C, comparison of the CBL3 conformation in the
Ca^2+-bound (blue) and Ca^2+-free (gray) form of the C2A domain.
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