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Figure 4.
Figure 4. Specific Recognition of the B Subunit for the PP2A
Scaffold Subunit
(A) A stereo view of the atomic
interactions between the β2C-β2D hairpin arm of Bα and HEAT
repeats 1 and 2 of Aα. This interface is dominated by van der
Walls contacts.
(B) A stereo view of the recognition
between the bottom face of Bα and HEAT repeats 3–7. This
interface contains a number of hydrogen bonds, which are
represented by red dashed lines.
(C) Structural comparison
of the PP2A holoenzymes involving the regulatory B/B55/PR55 and
B′/B56/PR61 subunits.
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