Figure 4 - full size

 

Figure 4.
Comparison of ICAM-2, NEP, and CD44 peptides bound to the FERM domain. Shown is superposition of ICAM-2 (magenta) from the FERM-ICAM-2 complex (28) and NEP (green) from the FERM-NEP complex (31) on the FERM-CD44 complex. The N-terminal extensions of ICAM-2 and CD44 or the C terminus of NEP that would be linked to the transmembrane helix in the plasmamembrane are indicated with dotted lines.

The above figure is reprinted from an Open Access publication published by the ASBMB: J Biol Chem (2008, 283, 29602-29612) copyright 2008.