Figure 4 - full size

 

Figure 4.
Surface representations of LIR proteins and their binding partners. Contact surfaces (≤4.0 Å) are highlighted in yellow. (A) UL18, UL18/LIR-1, and LIR-1. An asterisk marks the position of a LIR-1 loop (residues 148–154) that is disordered in the UL18/LIR-1 complex structure. (B) HLA-A2, HLA-A2/LIR-1, and LIR-1 (PDB ID code 1P7Q). (C) HLA-G, HLA-G/LIR-2, and LIR-2 (PDB ID code 2DYP).