Figure 4 - full size

 

Figure 4.
FIGURE 4. Calcium binding to Tcad1. For this representation, the chemical shift changes in ^1H-^15N-HSQC of Tcad1 with different concentrations of Ca^2+ (supplemental Fig. S4) have been mapped onto a space-filling model of Tcad1 (middle and right). Strong (red) and weak (orange) chemical shift changes are observed only for residues in proximity to the calcium binding sites (residues with green colored side chains in the ribbon representation to the left, see also Fig. 1B). Residues colored in yellow shift only very weakly.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2008, 283, 23485-23495) copyright 2008.