Figure 4 - full size

 

Figure 4.
Figure 4. The Linker Between the Kinase and SAM Domains Binds into a Complementary Pocket on the C-terminal Lobe of the Kinase Domain
An electrostatic surface was generated using APBS (Baker et al., 2001) using a gradient from −10 to 10 keT. Shown in cartoon and stick representation is the model for KIN ANP in firebrick red; this model contains the most ordered linker region comprising residues 885–906. Highlighted is the complementary surface made up by Tyr841, Leu901, and Leu903.

The above figure is reprinted by permission from Cell Press: Structure (2008, 16, 873-884) copyright 2008.