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Figure 4.
Figure 4. Distribution of CaM N- and C-Domain Contacts in the
CaM-NR1C1p Complex
(A) N-domain residues ≤ 4.5 Å of
NR1C1p shown as sticks; 17 contacts were made with NR1 residues
875–885 (gray), and 19 contacts were made with residues
885–896 (black).
(B) Sequence map of CaM residues ≤ 4.5
Å of NR1C1p. Residues in NR1C1p that make the highest
number of contacts exclusively with the C domain (F880) and the
N domain (T886) are boxed; the ER retention signal is
underlined.
(C) C-domain residues ≤ 4.5 Å of NR1C1p
shown as sticks; 27 contacts were made with residues 875–885,
and 7 contacts were made with residues 885–896. Ca^2+ ions and
binding sites (yellow in [A] and [C]) are designated I, II, III,
and IV.
The figure was made with MacPymol.
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