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Figure 4.
Figure 4. Layered Appearance of COPII Coat Proteins in a
Model of Sec23/24•Sar1 Bound to Sec31
The ribbon
representation on the left is a side view of Sec23/24•Sar1
complexed with the Sec31 active fragment. Sec23 is orange, Sar1
is red, GppNHp is blue, the Sec31 fragment is blue, and Sec24 is
green. This is a composite model that includes Sec24 taken from
a Sec23/24 crystal structure determined previously (Bi et al.,
2002). The gray line indicates the curvature of membrane
vesicle, and the dotted red line suggests the attachment of Sar1
to membrane via its N-terminal sequence. The view on the right
is rotated 90° to show the membrane-distal surface in
space-filling representation (same orientation as in Figure 3).
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