Figure 4.
(a) Ribbon representation of SPF45-UHM with stick
representation of SF3b155-ULM5 peptide. (b) Details of the
molecular recognition of SPF45-UHM and SF3b155-ULM5.
Experimental omit-electron density map contoured at 1.8 (blue)
surrounds a stick representation of residues 337–342 of the
SF3b155 peptide (orange). SPF45-UHM residues involved in ULM
coordination are shown in gray. (c) Structures of the
U2AF65-UHM–SF1-ULM complex (left, PDB 1O0P) and the
U2AF35-UHM–U2AF65-ULM complex (right, PDB 1JMT).
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(2007,
14,
620-629)
copyright 2007.
(blue)
surrounds a stick representation of residues 337–342 of the
SF3b155 peptide (orange). SPF45-UHM residues involved in ULM
coordination are shown in gray. (c) Structures of the
U2AF65-UHM–SF1-ULM complex (left, PDB 1O0P) and the
U2AF35-UHM–U2AF65-ULM complex (right, PDB 1JMT).