Figure 4.
Figure 4. Thermodynamics of substrate and product binding by
SENP1 C603A. ITC was used to study the thermodynamic changes
effected by binding of SENP1 to SUMO-1-FL, SUMO-2-FL,
RanGAP1–SUMO-1, SUMO-1-GG, SUMO-2-GG or RanGAP1 (as
indicated). Experiments were repeated on three separate
occasions with very similar results. Thermodynamic parameters
are indicated in Table 1.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Mol Biol
(2006,
13,
1069-1077)
copyright 2006.
