Figure 4 - full size

 

Figure 4.
Figure 4. Divergent Stereoview of the Superposition of the Active Sites of FeeM and AANAT
The backbone atoms and side chains believed to be important for catalysis in AANAT are shown in green. The amide portion (i.e., the bond formed during catalysis) of the product analog bound to AANAT is shown as a ball-and-stick model in green. The “proton wire” is shown in red. FeeM is shown in cyan with the amide portion of N-lauroyl tyrosine shown as a ball and stick in dark gray.

The above figure is reprinted by permission from Cell Press: Structure (2006, 14, 1425-1435) copyright 2006.